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Hudson Yards 15, New York, NY 10001

The Effect Poster
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Photo by Ion Fet on Unsplash

The Effect

4.5 star rating4.5 star rating4.5 star rating4.5 star rating4.5 star rating

March 3 - 31, 2024

Critic's Pick: Paapa Essiedu and Taylor Russell are terrific (in) Lucy Prebble's thought-provoking play.

The New York Times

Why See The Effect?

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Lucy Prebble's The Effect was the toast of London on its West End debut in 2012, picking up the UK Critics Choice Award for Best New Play. Now returning to New York in this stunning revival from The Jamie Lloyd Company with a strictly limited run at The Shed's Griffin Theatre with the incredible Paapa Essiedu (I May Destroy You, Hamlet) and Taylor Russell (Bones and All) reprising their roles from London's National Theatre run alongside Kobna Holdbrook-Smith and Michele Austin.

What is the story?

Connie and Tristan are two guinea pigs testing a new drug RLU37. It's an antidepressant, which is of particular interest to their depression-prone supervising psychiatrist Dr Lorna James. As the test continues, RLU37 seems to have some rather unforeseen effect - Connie and Tristan fall madly in love with each other. While Lorna's boss is jubilant that they might have discovered 'a Viagra for the heart', she's skeptical whether the couple's romance is chemically influenced at all. And if it is, does that make it any less real or true for the people involved?

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Additional Information


Previews from: 3 March 2024

Opening night: 13 March 2024


This production contains strong language and adult themes. There are strobe/flashing lights, smoke, and haze effects, with some loud music. Some scenes include sexual content, physical aggression, depictions of seizures, and references to depression, anxiety, and suicide.

Run time

One hour and 40 minutes with no intermission


You may be required to wear a mask during this performance. Please contact the venue directly for more information.

Cast and Creative


Paapa Essiedu as Tristan
Taylor Russell as Connie
Kobna Holdbrook-Smith as Dr. Toby Sealey
Michele Austin as Dr. Lorna James 


Written by Lucy Prebble
Directed by Jamie Lloyd
Set and costume design by Soutra Gilmour
Lighting design by Jon Clark
Composition by Michael 'Mikey J' Asante
Sound design by George Dennis
Movement direction by Sarah Golding and Yukiko Masui (SAY)
Fight direction by Kate Waters
Intimacy coordination by Ingrid Mackinnon
 Casting by Alastair Coomer

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